Twelve hour anaesthesia in a patient with epidermolysis bullosa. Can J Anaesth 1995 Aug;42(8):735-9
Date
08/01/1995Pubmed ID
7586115DOI
10.1007/BF03012674Scopus ID
2-s2.0-0029153666 (requires institutional sign-in at Scopus site) 14 CitationsAbstract
Epidermolysis bullosa (EB), an inherited disorder presents clinically with recurrent cutaneous blister formation with possible involvement of mucous membranes and other organs. The sequelae of this disease pose multiple challenges to the anaesthetist and operating room team. Recent literature describes several anaesthetic techniques for the short surgical procedures this patient population may undergo. We describe the anaesthetic technique employed in a 28-yr-old women with recessive dystrophic epidermolysis bullosa who underwent 12 hr reconstructive surgery followed by a review of the literature that includes a recent description of the possible association of EB with at least two distinct neuromuscular diseases. A detailed description of airway and skin management is described in addition to preoperative concerns. We conclude that a prolonged operative procedure can be undertaken successfully in this population with minimal sequelae involving skin integrity and airway management.
Author List
Yonker-Sell AE, Connolly LAAuthor
Lois A. Connolly MD Emeritus Professor in the Anesthesiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAnesthesia, General
Epidermolysis Bullosa Dystrophica
Female
Genes, Recessive
Hand
Humans
Neuromuscular Diseases
Preoperative Care
Respiration
Skin Care
Surgical Flaps
Syndactyly
Time Factors
