Wilms Tumor: Challenges and Newcomers in Prognosis. Surg Pathol Clin 2020 Dec;13(4):683-693
Date
11/14/2020Pubmed ID
33183727DOI
10.1016/j.path.2020.08.007Scopus ID
2-s2.0-85096082821 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
Wilms tumor is the most common renal tumor of childhood. It is a biologically and morphologically diverse entity, with ongoing studies contributing to our understanding of the pathobiology of various subgroups of patients with Wilms tumor. The interplay of histologic examination and molecular interrogation is integral in prognostication and direction of therapy. This review provides an overview of some of the challenging aspects and pitfalls in pathologic assessment of Wilms tumor, along with discussion of current and up-and-coming markers of biological behavior with prognostic significance.
Author List
Parsons LNAuthor
Lauren Parsons MD Associate Professor in the Pathology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Biomarkers, TumorChild
Humans
Kidney Neoplasms
Neoplasm Staging
Prognosis
Wilms Tumor