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Retinopathy of prematurity: an analysis of risk factors. J Formos Med Assoc 1993 May;92(5):440-5



Pubmed ID



In order to investigate the possible clinical factors related to the occurrence of retinopathy of prematurity (ROP), 37 very-low-birth-weight infants documented to have ROP were compared to a group of 50 controls during the period from July 1988 to December 1991. The results revealed that: 1) the overall occurrence rate of ROP was 42.5% (37/87), with a higher occurrence rate in the less mature weight-stratified subgroup; 2) patients in the lower stages of ROP generally regressed during the follow-up, while nearly all of those in the higher stages eventually progressed and received surgical intervention; and 3) after multiple logistic regression analysis, the consistently significant factors were birth weight, duration of PaO2 > or = 80 mmHg, ventilation time > or = five days and a blood exchange transfusion. It is suggested that regular examination for ROP in high-risk premature infants is important in combination with other monitoring modalities in neonatal intensive care units to reduce the possible complications and sequelae of ROP.

Author List

Chou YH, Teng RJ, Yau KI, Yang CM


Ru-Jeng Teng MD Associate Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Infant, Newborn
Regression Analysis
Retinopathy of Prematurity
Retrospective Studies
Risk Factors
Transfusion Reaction
jenkins-FCD Prod-478 d1509cf07a111124a2d122fd3df854cc0b993c00