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Identification of alpha1-acid glycoprotein, alpha2-macroglobulin and antithrombin III as components of normal and malignant human tissues. Clin Chim Acta 1977 Feb 15;75(1):143-8

Date

02/15/1977

Pubmed ID

66107

DOI

10.1016/0009-8981(77)90510-1

Scopus ID

2-s2.0-0017367867 (requires institutional sign-in at Scopus site)   13 Citations

Abstract

alpha1-Acid glycoprotein, alpha2-macroglobulin, and antithrombin III have been identified, by immunological means, as components of the 90000 X g supernatant fraction of malignant and adjacent normal human breast, colon, and anal tissues, as well as malignant stomach and ileum. Malignant lung tissue only contained alpha1-acid glycoprotein. These protease inhibitors are immunologically equivalent to those present in human plasma.

Author List

Twining SS, Brecher AS

Author

Sally S. Twining PhD Assistant Dean, Professor in the Biochemistry department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Antithrombins
Humans
Neoplasms
Orosomucoid
alpha-Macroglobulins