Faculty Collaboration Database

Trends and Inpatient Outcomes of Primary Heart Failure Hospitalizations with a Concurrent Diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (from The National Inpatient Sample Database from 2004 to 2014). Am J Cardiol 2021 Jul 01;150:69-76

Date

05/19/2021

Pubmed ID

34001343

DOI

10.1016/j.amjcard.2021.03.054

Scopus ID

2-s2.0-85106262798 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

Heart failure (HF) and acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are considered significant causes of morbidity and mortality worldwide. Concurrent presentation of HF with AECOPD can pose a diagnostic challenge due to an overlap in symptomatology. We queried the National Inpatient Sample (NIS) database to assess outcomes of HF hospitalizations with a secondary diagnosis of AECOPD. We performed a retrospective analysis of discharge data from the Healthcare Cost Utilization Project NIS between January 1, 2004, and December 31, 2014, with a primary diagnosis of HF with and without a secondary diagnosis of AECOPD. Data was abstracted from the NIS using International Classification of Disease 9 codes. Primary outcomes included mortality, length of stay, and inflation-adjusted cost of stay. During 2004-2014, a total of (n = 10,392,628) HF hospitalizations were identified without a secondary diagnosis of AECOPD while (n = 989,713) HF hospitalizations were identified with a secondary diagnosis of AECOPD. We identified higher mortality (3.25% vs 3.56%, p <0.001), length of stay (5.2 vs 6.1 days, p <0.001) and inflation-adjusted cost of stay (12,562 vs 13,072 USD, p <0.001) in HF hospitalizations with AECOPD when compared to HF without AECOPD from 2004 to 2014. We presented AECOPD as an independent predictor of mortality in patients admitted for HF. In conclusion, further interdisciplinary collaboration between pulmonologists and cardiologists is needed for the identification and stratification of patients who present with concurrent HF and COPD for better outcomes.

Author List

Kichloo A, Minhas AMK, Jamal S, Shaikh AT, Albosta M, Singh J, Khan MZ, Aljadah M, Wani F, Wazir MHK, Kanjwal K

Author

Michael M. Aljadah MD Instructor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Aged
Databases, Factual
Female
Heart Failure
Hospital Charges
Hospital Mortality
Hospitalization
Humans
Inpatients
Length of Stay
Male
Pulmonary Disease, Chronic Obstructive
Retrospective Studies
Symptom Flare Up
United States