Anaesthetic and postanaesthetic effect of isoflurane on the multiple-unit activity of the immature rat hippocampus. Fiziol Zh (1994) 2011;57(1):17-20
Date
04/26/2011Pubmed ID
21513222DOI
10.15407/fz57.01.017Scopus ID
2-s2.0-79957717683 (requires institutional sign-in at Scopus site) 1 CitationAbstract
We investigated anesthetic and postanaesthetic effect of isoflurane on the multi-unit activity (MUA) in the CA3 region of immature rat hippocampus. MUA amplitude did not significantly change during application of isoflurane. On the other hand MUA frequency significantly decreased during the anesthesia. After isoflurane discontinuation two phases of MUA frequency recovery were observed: initial rapid increase followed by a slower recovery to the control level. Comparison of recovering period of the receptor mediated systems and spontaneous field activity from isoflurane anesthesia is discussed.
Author List
Isaeva EV, Isaev DSAuthor
Olena Isaeva PhD Assistant Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Action PotentialsAnesthesia
Anesthetics, Inhalation
Animals
CA3 Region, Hippocampal
In Vitro Techniques
Isoflurane
Pyramidal Cells
Rats
Rats, Sprague-Dawley
Time Factors
Volatilization