Reporting results of obstructive sleep apnea syndrome surgery trials. Otolaryngol Head Neck Surg 2011 Apr;144(4):496-9
Date
04/16/2011Pubmed ID
21493223Pubmed Central ID
PMC5951288DOI
10.1177/0194599810396791Scopus ID
2-s2.0-84855537207 (requires institutional sign-in at Scopus site) 39 CitationsAbstract
Obstructive sleep apnea syndrome surgery studies largely evaluate single procedures or procedure combinations in case series designs, but it can be difficult to compare results across studies. The authors present a standardized format for presentation of surgical study results to facilitate pooled analyses and subgroup analyses. The format includes thorough characterization of baseline subject characteristics and the use of outcome measures that reflect the spectrum of obstructive sleep apnea and its consequences. As the apnea-hypopnea index is the most common, albeit controversial, primary outcome measure in obstructive sleep apnea syndrome surgery studies, the authors propose analysis and reporting standards to facilitate understanding its role as an outcome measure. Because surgical outcomes vary according to subject characteristics, investigators should also evaluate the potential association between baseline subject characteristics and outcomes.
Author List
Kezirian EJ, Weaver EM, Criswell MA, de Vries N, Woodson BT, Piccirillo JFAuthor
B Tucker Woodson MD Chief, Professor in the Otolaryngology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ApneaData Interpretation, Statistical
Humans
Sleep Apnea, Obstructive