Faculty Collaboration Database

Relationship of ovarian neoplasms and body mass index. J Reprod Med 2005 Aug;50(8):595-602

Date

10/14/2005

Pubmed ID

16220765

Scopus ID

2-s2.0-23944512214 (requires institutional sign-in at Scopus site)   9 Citations

Abstract

OBJECTIVE: To describe the distribution of benign and malignant ovarian neoplasms among overweight and obese women.

STUDY DESIGN: A review of patients who presented with a preoperative diagnosis of a pelvic mass between 1996 and 2001 was performed; 1,096 patients were identified. Patients were stratified by body mass index into 3 groups: normal weight, overweight and obese. The pathologic findings in the 3 groups were compared.

RESULTS: Complete follow-up was available on 668 patients. Overall, 248 patients were obese, 176 were overweight, and 244 had a normal body mass index. A significant difference existed in the pathologic findings in the 3 groups (p = 0.049). Women with normal body mass indices were more likely to have malignant ovarian tumors (35.2%) than were the overweight (23.9%) and obese (25.8%) women. Conversely, borderline ovarian tumors were less frequent in women with body mass indices of <25 (5.7%) than in the overweight (13.1%) and obese (10.9%) patients. Benign ovarian neoplasms occurred in 20-25% of the women.

CONCLUSION: Significant differences exist in the distribution of ovarian neoplasms among women with different body mass indices. Obese women are more likely to have ovarian tumors of low malignant potential, while women with normal body mass indices more commonly have invasive ovarian tumors. Body mass index may be an important factor in preoperative counseling and risk assessment.

Author List

Wright JD, Powell MA, Mutch DG, Rader JS, Gibb RK, Gao F, Herzog TJ

Author

Janet Sue Rader MD Chair, Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Aged
Aged, 80 and over
Body Mass Index
Body Weight
Child
Cohort Studies
Female
Humans
Middle Aged
Neoplasm Invasiveness
Neoplasm Staging
Obesity
Ovarian Cysts
Ovarian Neoplasms
Retrospective Studies
Risk Factors