Five days of fever and myocardial inflammation. SAGE Open Med Case Rep 2021;9:2050313X211050891
Date
10/15/2021Pubmed ID
34646566Pubmed Central ID
PMC8504640DOI
10.1177/2050313X211050891Scopus ID
2-s2.0-85116615830 (requires institutional sign-in at Scopus site)Abstract
Multisystem inflammatory syndrome in children is an emerging pediatric illness associated with severe acute respiratory syndrome coronavirus 2 infection. The syndrome is rare, and evidence-based guidelines are lacking. This report reviews a patient who presented for medical care multiple times early in the course of his illness, thus offering near-daily documentation of symptoms and laboratory abnormalities. The patient did not have thrombocytopenia, anemia, or myocardial inflammation until the fifth day of fever. These laboratory abnormalities coincided with the onset of rash, conjunctival injection, vomiting, and diarrhea: clinical signs that could serve as indicators for when to obtain blood tests. The timing of this patient's onset of multisystem involvement suggests that testing for multisystem inflammatory syndrome in children after only 24 h of fever, as the Centers for Disease Control and Prevention recommends, may yield false-negative results. Testing for multisystem inflammatory syndrome in children after 4 days of fever may be more reliable.
Author List
Coleman KD, Benz P, Parikh NS, Thomas DG, Segar D, Block J, Schultz MLAuthors
Joseph Block MD Associate Professor in the Pediatrics department at Medical College of WisconsinKeli D. Coleman MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
Megan L. Schultz MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
David Segar MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
Danny G. Thomas MD, MPH Professor in the Pediatrics department at Medical College of Wisconsin
