Medical College of Wisconsin
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Evaluation of regional cerebral blood flow in massive intracerebral calcifications. J Nucl Med 1995 Apr;36(4):610-2

Date

04/01/1995

Pubmed ID

7699451

Scopus ID

2-s2.0-0028921378 (requires institutional sign-in at Scopus site)   53 Citations

Abstract

Fahr's disease is histopathologically characterized by massive bilateral calcifications of the cerebral basal ganglia, the dentate nuclei of the cerebellum and both the cerebral and cerebellar cortices. We report a case of Fahr's disease in which a 99mTc-hexamethyl-propylenamine oxime (99mTc-HMPAO) brain SPECT study was used to evaluate regional cerebral blood flow to the calcified regions. There was markedly decreased perfusion to the basal ganglia bilaterally as well as decreased perfusion to the cerebral cortices that correlated well with the patient's clinical condition.

Author List

Uygur GA, Liu Y, Hellman RS, Tikofsky RS, Collier BD

Author

Robert Hellman MD Emeritus Professor in the Radiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Basal Ganglia
Basal Ganglia Diseases
Brain
Calcinosis
Cerebellar Nuclei
Cerebral Cortex
Cerebrovascular Circulation
Humans
Male
Organotechnetium Compounds
Oximes
Technetium Tc 99m Exametazime
Tomography, Emission-Computed, Single-Photon