Lentigo maligna: diagnosis and treatment. Clin Plast Surg 2010 Jan;37(1):35-46
Date
11/17/2009Pubmed ID
19914456DOI
10.1016/j.cps.2009.08.006Scopus ID
2-s2.0-70449382397 (requires institutional sign-in at Scopus site) 26 CitationsAbstract
Lentigo maligna is an overgrowth of atypical melanocytes at the dermal-epidermal junction also known as melanoma in situ. Left untreated, these lesions can continue to grow, resulting in dermal invasion and progression to lentigo maligna melanoma. Many operative and nonoperative treatments have been developed with the goals of preserving function and cosmesis while at the same time addressing the diffuse nature of these lesions. Previous recommendations have led plastic surgeons to commonly perform wide local excision with 5 mm margins. More recent literature has suggested that in many cases this treatment can result in high recurrence rates. This has led to margin control procedures becoming the treatment of choice for these lesions.
Author List
Bosbous MW, Dzwierzynski WW, Neuburg MAuthor
William W. Dzwierzynski MD Professor in the Plastic Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
HumansHutchinson's Melanotic Freckle
Melanoma
Mohs Surgery
Neoplasm Recurrence, Local
Skin Neoplasms
