[Changes in the surface topography of 3T3 cells as affected by epidermal growth factor and insulin]. Tsitologiia 1986 Dec;28(12):1316-21
Date
12/01/1986Pubmed ID
3547958Scopus ID
2-s2.0-0022989789 (requires institutional sign-in at Scopus site)Abstract
Using scanning electron microscopy, a study was made of the surface topography of the Swiss 3T3 cells whose proliferation was arrested in the serum-less (0.5%) medium due to the application of the epidermal growth factor and insulin for, respectively, 10 and 30 minutes. The early cell response on the growth factors was diminishing the number of microvilli and appearance of plasma membrane invaginations. The degree of quiescent cell spreading under the action of the two above factors was different, since the epidermal growth factor, unlike insulin, induced cell reaction.
Author List
Skopicheva VI, Skopichev VG, Sorokin AB, Nikol'skiĭ NNAuthor
Andrey Sorokin PhD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsCell Division
Cell Line
Cells, Cultured
Epidermal Growth Factor
Insulin
Mice
Mice, Inbred Strains
Microscopy, Electron, Scanning
Surface Properties