[Characteristics of the surface topography of Swiss 3T3 cells with altered proliferative activity]. Tsitologiia 1986 Jul;28(7):687-92
Date
07/01/1986Pubmed ID
3532463Scopus ID
2-s2.0-0022745453 (requires institutional sign-in at Scopus site)Abstract
A scanning electron microscope study of the Swiss 3T3 cell surface topography was made in association with changes in proliferative activity. On the phase of logarithmic growth the cell shape is similar to that of an actively migrating fibroblast. When the growth promoting factors are depleted, the cells are seen spread and forming numerous cell-to-cell contacts. The stimulation of cell proliferation induced by a 10% serum or by epidermal growth factor is associated with a disturbance of cell interaction because of the centripetal cell contraction.
Author List
Skopicheva VI, Skopichev VG, Sorokin ABAuthor
Andrey Sorokin PhD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsCell Communication
Cell Division
Cells, Cultured
Epidermal Growth Factor
Fibroblasts
Immune Sera
Insulin
Mice
Microscopy, Electron, Scanning
Surface Properties