Medical College of Wisconsin
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[Characteristics of the surface topography of Swiss 3T3 cells with altered proliferative activity]. Tsitologiia 1986 Jul;28(7):687-92

Date

07/01/1986

Pubmed ID

3532463

Scopus ID

2-s2.0-0022745453 (requires institutional sign-in at Scopus site)

Abstract

A scanning electron microscope study of the Swiss 3T3 cell surface topography was made in association with changes in proliferative activity. On the phase of logarithmic growth the cell shape is similar to that of an actively migrating fibroblast. When the growth promoting factors are depleted, the cells are seen spread and forming numerous cell-to-cell contacts. The stimulation of cell proliferation induced by a 10% serum or by epidermal growth factor is associated with a disturbance of cell interaction because of the centripetal cell contraction.

Author List

Skopicheva VI, Skopichev VG, Sorokin AB

Author

Andrey Sorokin PhD Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Cell Communication
Cell Division
Cells, Cultured
Epidermal Growth Factor
Fibroblasts
Immune Sera
Insulin
Mice
Microscopy, Electron, Scanning
Surface Properties