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Left Atrial Appendage Occlusion as an Alternative to Anticoagulants in Ibrutinib-Induced Hemorrhagic Pericardial Effusion. JACC Case Rep 2022 Jun 15;4(12):751-754

Date

06/24/2022

Pubmed ID

35734528

Pubmed Central ID

PMC9207956

DOI

10.1016/j.jaccas.2022.01.027

Scopus ID

2-s2.0-85132437869 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

Bleeding tendency increases with concomitant use of ibrutinib and anticoagulants. Our patient presented with shortness of breath and was found to have a nonmalignant hemorrhagic pericardial effusion. Ibrutinib was resumed, and percutaneous left atrial appendage occlusion was performed as a substitute for the chemical anticoagulation to decrease the drug-drug interaction. (Level of Difficulty: Intermediate.).

Author List

Jeelani H, Sheikh MM, Tahir N, Ying G, Prasad S, Yaremko M, Gill J

Author

Muhammad Mubbashir Sheikh MD Assistant Professor in the Medicine department at Medical College of Wisconsin