Inflammatory pseudotumor of the pancreas. Int J Pancreatol 1995 Dec;18(3):277-83
Date
12/01/1995Pubmed ID
8708401DOI
10.1007/BF02784953Scopus ID
2-s2.0-0029583891 (requires institutional sign-in at Scopus site) 24 CitationsAbstract
We describe a rare example of inflammatory pseudotumor of the pancreas in a 42-yr-old woman, which developed following chemotherapy for lymphoma of the uterine cervix. The patient had developed fatigue, weight loss, abdominal pain, and anemia; abdominal CT scan showed a large mass in the pancreas. Examination of the resected specimen revealed a fleshy, well-circumscribed, 7-cm mass. Histologically, there was a hypocellular to moderately hypercellular, bland spindle-cell proliferation admixed with a prominent infiltrate of lymphocytes, histiocytes, and plasma cells. The spindle cells were vimentin positive but negative for muscle markers; electron microscopy revealed only fibroblastic cells. DNA analysis revealed a diploid population with low S-phase fraction. The patient was well at 6-mo follow-up. It is important for the pathologist to be aware of the existence of this entity in unusual locations such as the pancreas so as to avoid a mistaken diagnosis of malignancy.
Author List
Kroft SH, Stryker SJ, Winter JN, Ergun G, Rao MSAuthor
Steven Howard Kroft MD Chair, Professor in the Pathology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultDNA
Female
Granuloma, Plasma Cell
Humans
Immunohistochemistry
Pancreatic Diseases
