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ALSUntangled #62: vitamin C. Amyotroph Lateral Scler Frontotemporal Degener 2022 Aug;23(5-6):476-479

Date

07/01/2021

Pubmed ID

34187257

DOI

10.1080/21678421.2021.1946088

Scopus ID

2-s2.0-85134444415 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

Vitamin C is one of the most common supplements taken by people with ALS. As an antioxidant, it has a plausible mechanism for slowing disease progression and there are some flawed pre-clinical studies and case reports suggesting benefit. However, a small human trial showed no benefit. Given this negative trial, we do not currently advise vitamin C as an ALS treatment.

Author List

Bedlack R, Barkhaus P, Carter G, Crayle J, Mcdermott C, Pattee G, Polak M, Salmon K, Wicks P

Author

Paul E. Barkhaus MD Professor in the Neurology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Amyotrophic Lateral Sclerosis
Ascorbic Acid
Clinical Trials as Topic
Dietary Supplements
Humans
Treatment Outcome
Vitamins