ALSUntangled #62: vitamin C. Amyotroph Lateral Scler Frontotemporal Degener 2022 Aug;23(5-6):476-479
Date
07/01/2021Pubmed ID
34187257DOI
10.1080/21678421.2021.1946088Scopus ID
2-s2.0-85134444415 (requires institutional sign-in at Scopus site) 1 CitationAbstract
Vitamin C is one of the most common supplements taken by people with ALS. As an antioxidant, it has a plausible mechanism for slowing disease progression and there are some flawed pre-clinical studies and case reports suggesting benefit. However, a small human trial showed no benefit. Given this negative trial, we do not currently advise vitamin C as an ALS treatment.
Author List
Bedlack R, Barkhaus P, Carter G, Crayle J, Mcdermott C, Pattee G, Polak M, Salmon K, Wicks PAuthor
Paul E. Barkhaus MD Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Amyotrophic Lateral SclerosisAscorbic Acid
Clinical Trials as Topic
Dietary Supplements
Humans
Treatment Outcome
Vitamins