Value of amnioinfusion in reducing meconium aspiration syndrome. Am J Perinatol 1993 Jan;10(1):43-5
Date
01/01/1993Pubmed ID
8442798DOI
10.1055/s-2007-994699Scopus ID
2-s2.0-0027410050 (requires institutional sign-in at Scopus site) 18 CitationsAbstract
Infusing normal saline into the uterine cavity, or amnioinfusion, is used to reduce the risk of meconium aspiration syndrome in babies born to women in whom the pregnancy is complicated by thick, meconium-stained amniotic fluid. In this retrospective review of 436 such pregnancies amnioinfusion was performed in 110. In 18.2% of infants in the amnioinfusion group meconium was found in the trachea compared with 29.1% of infants in the untreated group. In the treated group respiratory distress occurred in 2.7%, and meconium aspiration syndrome in 1.8%, whereas in the untreated group these frequencies were 10.1 and 5.5%, respectively. We conclude that saline amnioinfusion in pregnancies complicated by thick, meconium-stained amniotic fluid reduces the risk of respiratory distress in the newborn.
Author List
Uhing MR, Bhat R, Philobos M, Raju TNAuthor
Michael R. Uhing MD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAmnion
Female
Humans
Infant, Newborn
Meconium Aspiration Syndrome
Pregnancy
Respiratory Distress Syndrome, Newborn
Retrospective Studies
Risk Factors
Sodium Chloride