Faculty Collaboration Database

Regional brain tissue pressure gradients created by expanding extradural temporal mass lesion. J Neurosurg 1997 Mar;86(3):505-10

Date

03/01/1997

Pubmed ID

9046308

DOI

10.3171/jns.1997.86.3.0505

Scopus ID

2-s2.0-0031029118 (requires institutional sign-in at Scopus site)   38 Citations

Abstract

A porcine model of regional intracranial pressure was used to compare regional brain tissue pressure (RBTP) changes during expansion of an extradural temporal mass lesion. Measurements of RBTP were obtained by placing fiberoptic intraparenchymal pressure monitors in the right and left frontal lobes (RF and LF), right and left temporal lobes (RT and LT), midbrain (MB), and cerebellum (CB). During expansion of the right temporal mass, significant RBTP gradients developed in a reproducible pattern: RT > LF = LT > RF > MB > CB. These gradients appeared early, widened as the volume of the mass increased, and persisted for the entire duration of the experiment. The study indicates that RBTP gradients develop in the presence of an extradural temporal mass lesion. The highest RBTP was recorded in the ipsilateral temporal lobe, whereas the next highest was recorded in the contralateral frontal lobe. The RBTP that was measured in either frontal lobe underestimated the temporal RBTP. These results indicated that if a frontal intraparenchymal pressure monitor is used in a patient with temporal lobe pathology, the monitor should be placed on the contralateral side and a lower threshold for therapy of increased intracranial pressure should be adopted. Furthermore, this study provides further evidence that reliance on a single frontal intraparenchymal pressure monitor may not detect all areas of elevated RBTP.

Author List

Wolfla CE, Luerssen TG, Bowman RM

Author

Christopher E. Wolfla MD Professor in the Neurosurgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Brain
Brain Diseases
Cerebellum
Disease Models, Animal
Fiber Optic Technology
Frontal Lobe
Intracranial Pressure
Mesencephalon
Monitoring, Physiologic
Pseudotumor Cerebri
Reproducibility of Results
Swine
Temporal Lobe
Time Factors