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Congenital lupus erythematosus presenting at birth with widespread erosions, pancytopenia, and subsequent hepatobiliary disease. Pediatr Dermatol 2010;27(1):109-11

Date

03/05/2010

Pubmed ID

20199433

DOI

10.1111/j.1525-1470.2009.01057.x

Scopus ID

2-s2.0-77649124704 (requires institutional sign-in at Scopus site)   16 Citations

Abstract

Neonatal lupus erythematosus is an uncommon disease caused by transplacental passage of maternal anti-Ro (SS-A), anti-LA (SS-B), or anti-U1RNP antibodies. Cutaneous findings of neonatal lupus are variable, but annular, erythematous plaques occurring within a few weeks of birth are most typical. Cutaneous lesions of congenital onset lupus erythematosus can differ from that of neonatal lupus erythematosus, presenting with atrophy or scarring, and less commonly, erosions. We report an unusual case of congenital lupus erythematosus presenting at birth with widespread erosions, pancytopenia, and subsequent hepatobiliary disease.

Author List

Lynn Cheng C, Galbraith S, Holland K

Author

Kristen E. Holland MD Associate Professor in the Dermatology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Cholestasis
Female
Hepatomegaly
Humans
Hyperbilirubinemia, Neonatal
Infant
Infant, Newborn
Infant, Newborn, Diseases
Lupus Erythematosus, Cutaneous
Pancytopenia
Pregnancy
Pregnancy Complications
Skin