Long-term follow-up of iatrogenic phototoxicity. Arch Ophthalmol 1998 Jun;116(6):753-7
Date
06/25/1998Pubmed ID
9639443DOI
10.1001/archopht.116.6.753Scopus ID
2-s2.0-0031843241 (requires institutional sign-in at Scopus site) 57 CitationsAbstract
OBJECTIVE: To evaluate the outcomes of a group of patients who suffered iatrogenic phototoxic injury.
METHODS: The medical records of 24 patients (24 eyes) with iatrogenic phototoxicity from 3 medical centers were reviewed. We report the findings from long-term follow-up of these patients with particular attention to visual outcome, type and duration of procedure, and location of the phototoxic lesion.
RESULTS: Phototoxic injury occurred after anterior segment surgery in 20 eyes and after vitrectomy in 4 eyes. The mean duration of surgery was 109 minutes; there was no statistically significant difference in duration between the anterior segment procedures and the vitrectomies. Mean final visual acuity was 20/40 for all cases (range, 20/15 to counting fingers) and 20/25 for all anterior segment cases. In vitrectomized eyes, the mean final visual acuity was 20/900. Phototoxic lesions tended to spare the fovea after anterior segment surgery and involve the foveal center after vitrectomy.
CONCLUSIONS: In general, patients who suffer phototoxicity do well, and the prognosis is good for extrafoveal lesions. Foveal injury, which often occurs with vitrectomy, usually leads to a worse visual outcome. The development of choroidal neovascularization may have an effect on the ultimate visual outcome as well.
Author List
Postel EA, Pulido JS, Byrnes GA, Heier J, Waterhouse W, Han DP, Mieler WF, Guse C, Wipplinger WAuthor
Dennis Han MD Emeritus Professor in the Ophthalmology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedAged, 80 and over
Anterior Eye Segment
Female
Follow-Up Studies
Fundus Oculi
Humans
Iatrogenic Disease
Light
Male
Middle Aged
Prognosis
Prospective Studies
Radiation Injuries
Retina
Visual Acuity
Vitrectomy









