Faculty Collaboration Database

Calcium crystal-associated arthritides. Curr Opin Rheumatol 1998 May;10(3):273-7

Date

06/03/1998

Pubmed ID

9608333

DOI

10.1097/00002281-199805000-00020

Scopus ID

2-s2.0-0031861132 (requires institutional sign-in at Scopus site)   18 Citations

Abstract

Articular calcium-containing crystals cause calcium pyrophosphate dihydrate (CPPD) deposition disease, basic calcium phosphate (BCP)-associated syndromes, and calcium oxalate arthritis. During the past year, important contributions have been made to our understanding of CPPD- and BCP-related syndromes. Clinical studies of CPPD deposition disease underscore the importance of extra-articular and spinal CPPD deposits, and question the association between hypothyroidism and chondrocalcinosis. Laboratory reports add key information to our current paradigms of CPPD crystal formation and CPPD-induced inflammation. Several interesting new therapeutic interventions may arise from this work. A case collection of BCP-related syndromes emphasizes the need for considering this diagnosis in young healthy patients with acute arthritis or periarthritis.

Author List

Rosenthal AK

Author

Ann K. Rosenthal MD Associate Dean, Chief, Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adrenal Cortex Hormones
Calcium Pyrophosphate
Chondrocalcinosis
Crystallization
Gout
Humans
Osteoarthritis
Syndrome