Insulin and hypertensive cardiovascular disease. Curr Opin Cardiol 1996 Sep;11(5):483-9
Date
09/01/1996Pubmed ID
8889374DOI
10.1097/00001573-199609000-00006Scopus ID
2-s2.0-10144220636 (requires institutional sign-in at Scopus site) 10 CitationsAbstract
Resistance to insulin-stimulated glucose uptake is associated with several cardiovascular disease risk factors, including hypertension, dyslipidemia, and alterations of the blood clotting cascade that accentuate thrombosis. This constellation of risk factors may be recognized at young ages and is at least in part heritable. Recognition of this syndrome dictates that preventive and therapeutic strategies should address overall cardiovascular disease risk. In patients with hypertension or diabetes, additional clinical trials are required to identify those interventions that will most effectively reduce not only overall risk but also definitive cardiovascular disease endpoints.
Author List
Kotchen TA, Kotchen JM, O'Shaughnessy IMMESH terms used to index this publication - Major topics in bold
AdultCardiovascular Diseases
Child
Diabetes Mellitus
Female
Humans
Hypertension
Insulin Resistance
Male
Middle Aged
Risk Factors