Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

The pathology of the chronic lymphoid leukaemias. Blood Rev 1995 Dec;9(4):234-50

Date

12/01/1995

Pubmed ID

8839399

DOI

10.1016/s0268-960x(95)90015-2

Scopus ID

2-s2.0-0029597851 (requires institutional sign-in at Scopus site)   31 Citations

Abstract

The chronic lymphoid leukaemias, though they all possess relatively mature lymphoid phenotypes, are a diverse group of diseases at the clinical, morphological, immunophenotypical, and biological levels. Generally accepted entities within this category include B-cell chronic lymphocytic leukaemia of classical and mixed-cell types, B-cell and T-cell prolymphocytic leukaemia, hairy-cell leukaemia and hairy-cell variant, splenic lymphoma with circulating villous lymphocytes, large granular lymphocytic leukaemia, adult T-cell leukaemia/lymphoma syndrome, and leukaemic phases of malignant lymphomas of both B-cell and T-cell types. Recent advances have helped to differentiate these diseases, allowing the development of more specific therapy and more accurate prognostication. In this article, we review the pathological aspects of these diseases.

Author List

Kroft SH, Finn WG, Peterson LC

Author

Steven Howard Kroft MD Chair, Professor in the Pathology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Humans
Immunophenotyping
Leukemia, Hairy Cell
Leukemia, Lymphocytic, Chronic, B-Cell
Leukemia, Prolymphocytic
Leukemia, Prolymphocytic, T-Cell
Leukemia-Lymphoma, Adult T-Cell
Sezary Syndrome