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Cervical Syphilitic Lymphadenitis in a 29-Year-Old Female: A Case Report. Cureus 2023 Mar;15(3):e36065

Date

04/15/2023

Pubmed ID

37056520

Pubmed Central ID

PMC10092898

DOI

10.7759/cureus.36065

Abstract

Cervical lymphadenopathy is a common condition characterized by the enlargement of lymph nodes. It can have various causes, including infections, inflammatory conditions, and neoplastic processes. Syphilis, a sexually transmitted disease that progresses through multiple stages, can also be a rare cause of cervical lymphadenopathy, particularly in HIV-positive individuals. In this case report, we describe a patient presenting with throat pain, systemic symptoms, and cervical lymphadenopathy, initially clinically suggestive of lymphoma but ultimately determined to be caused by syphilis of unknown duration. This case highlights the importance of considering syphilis in the differential diagnosis of cervical lymphadenitis, particularly in patients with risk factors, such as intravenous drug use and HIV infection, and the need for a thorough evaluation of the patient's social and medical histories to diagnose and treat the condition accurately.

Author List

Bickford DD, Johnson P, Brahmbhatt N, Kroft S

Authors

Nupur Brahmbhatt MD Assistant Professor in the Medicine department at Medical College of Wisconsin
Steven Howard Kroft MD Chair, Professor in the Pathology department at Medical College of Wisconsin