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Association of neighborhood segregation with 6-year incidence of metabolic syndrome in the Hispanic community health study/study of Latinos. Ann Epidemiol 2023 Feb;78:1-8

Date

12/07/2022

Pubmed ID

36473628

Pubmed Central ID

PMC10127516

DOI

10.1016/j.annepidem.2022.11.003

Scopus ID

2-s2.0-85144390903 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

PURPOSE: Examine the association between neighborhood segregation and 6-year incident metabolic syndrome (MetSyn) in the Hispanic Community Health Study/Study of Latinos.

METHODS: Prospective cohort of adults residing in Miami, Chicago, the Bronx, and San Diego. The analytic sample included 6,710 participants who did not have MetSyn at baseline. The evenness and exposure dimensions of neighborhood segregation, based on the Gini and Isolation indices, respectively, were categorized into quintiles (Q). Racialized economic concentration was measured with the Index of Concentration at the Extremes (continuously and Q).

RESULTS: Exposure, but not evenness, was associated with higher disease odds (Q1 (lower segregation) vs. Q4, OR = 1.53, 95% CI = 1.082.17; Q5, OR = 2.29, 95% CI = 1.493.52). Economic concentrationprivilege (continuous OR = 0.87, 95% CI = 0.770.98), racial concentrationracialized privilege (Q1 (greater concentration) vs. Q2 OR = 0.75, 95% CI = 0.541.04; Q3 OR = 0.68, 95% CI = 0.441.05; Q4 OR = 0.68, 95% CI = 0.451.01; Q5 OR = 0.64, 95% CI = 0.420.98)(continuous OR = 0.93, 95% CI = 0.821.04), and racialized economic concentrationprivilege (i.e., higher SES non-Hispanic White, continuous OR = 0.86, 95% CI = 0.760.98) were associated with lower disease odds.

CONCLUSION: Hispanics/Latino adults residing in neighborhoods with high segregation had higher risk of incident MetSyn compared to those residing in neighborhoods with low segregation. Research is needed to identify the mechanisms that link segregation to poor metabolic health.

Author List

Pichardo CM, Pichardo MS, Gallo LC, Talavera GA, Chambers EC, Sanchez-Johnsen LAP, Pirzada A, Roy AL, Rodriguez C, Castañeda SF, Durazo-Arvizu RA, Perreira KM, Garcia TP, Allison M, Carlson J, Daviglus ML, Plascak JJ

Author

Lisa Sanchez-Johnsen PhD Center Associate Director, Professor in the Institute for Health and Humanity department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Humans
Incidence
Metabolic Syndrome
Prospective Studies
Public Health
Residence Characteristics