Faculty Collaboration Database

Comparison of cryotherapy and laser photocoagulation in stage III retinopathy of prematurity. J Formos Med Assoc 1997 Sep;96(9):734-9

Date

10/06/1997

Pubmed ID

9308328

Scopus ID

2-s2.0-0030922966 (requires institutional sign-in at Scopus site)   3 Citations

Abstract

Both cryotherapy and laser photocoagulation have been advocated for the treatment of stage III retinopathy of prematurity (ROP). In this retrospective study, we looked at which treatment was more effective and caused fewer complications. The outcomes of 23 patients (45 eyes) with stage III ROP treated with transconjunctival cryotherapy or indirect diode laser photocoagulation were reviewed. Group 1 (10 patients, 20 eyes) received cryotherapy and group 2 (13 patients, 25 eyes) received photocoagulation. In group 1, all had progressive ROP and one patient had bilateral neovascularization involving zone I. After treatment, 17 eyes had regression of ROP with good anatomic results, one eye had regression of the disease with mild to moderate macular ectopia and vessel traction, and two eyes (one patient) with zone I involvement advanced to stage V in 2 weeks. In group 2, 12 patients had threshold ROP, two had neovascularization involving zone I, and one patient had prethreshold zone I ROP. After treatment, 24 eyes had regression of ROP with good anatomic results and one eye had mild ectopic macula. Two eyes received two sessions of treatment. The results suggest that photocoagulation is at least as effective as cryotherapy and may be a favorable alternative for zone I ROP.

Author List

Yang CM, Chen MS, Tsou Yau KI, Teng RJ

Author

Ru-Jeng Teng MD Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Cryotherapy
Female
Humans
Infant
Infant, Newborn
Laser Coagulation
Male
Retinopathy of Prematurity
Retrospective Studies