Outcomes and complications of postoperative seroma cavities following soft-tissue sarcoma resection. Front Oncol 2024;14:1250069
Date
02/15/2024Pubmed ID
38357208Pubmed Central ID
PMC10864592DOI
10.3389/fonc.2024.1250069Scopus ID
2-s2.0-85184895863 (requires institutional sign-in at Scopus site)Abstract
INTRODUCTION: Seroma development is a known complication following extremity and trunk soft-tissue sarcoma (STS) resection. The purpose of this study is to evaluate and characterize seroma outcomes and the development of associated complications.
METHODS: A retrospective review of 123 patients who developed postoperative seromas following STS resection at a single institution was performed. Various patient and surgical factors were analyzed to determine their effect on overall seroma outcomes.
RESULTS: 77/123 seromas (62.6%) were uncomplicated, 30/123 (24.4%) developed infection, and 16/123 (13.0%) were symptomatic and required aspiration or drainage for symptom relief at an average of 12.2 months postoperatively. 65/123 (52.8%) seromas resolved spontaneously at an average time of 12.41 months. Seromas in the lower extremity (p=0.028), surgical resection volume >864 cm3, (p=<0.001) and initial seroma volume >42 cm3 (p=<0.001) increased the likelihood of infection. 90% of infected seromas developed the infection within the first three months following initial resection. No seromas which were aspirated or drained ultimately developed an infection following these procedures, though 50% recurred.
DISCUSSION: Most seromas following STS resection are uncomplicated and do not require intervention, though a large resection cavity >864 cm3 and a large seroma volume >42 cm3 are risk factors for complications.
Author List
Andryk LM, Neilson JC, Wooldridge AN, Hackbarth DA, Bedi M, Baynes KE, LoGiudice JA, Slusarczyk SM, King DMAuthors
Manpreet Bedi MD, MS Professor in the Radiation Oncology department at Medical College of WisconsinDavid M. King MD Chair, Professor in the Orthopaedic Surgery department at Medical College of Wisconsin
John C. Neilson MD Associate Professor in the Orthopaedic Surgery department at Medical College of Wisconsin
Adam Neal Wooldridge MD, MPH Assistant Professor in the Orthopaedic Surgery department at Medical College of Wisconsin
