Rosai-Dorman disease causing cervical myelopathy. Spine (Phila Pa 1976) 2000 Jun 01;25(11):1453-6
Date
06/01/2000Pubmed ID
10828930DOI
10.1097/00007632-200006010-00020Scopus ID
2-s2.0-0034212693 (requires institutional sign-in at Scopus site) 30 CitationsAbstract
STUDY DESIGN: A case report of a rare disease entity and review of the literature.
OBJECTIVES: To illustrate the occurrence of an unusual disease affecting the spine and spinal canal.
SUMMARY OF BACKGROUND DATA: Rosai-Dorman disease is considered an idiopathic benign lymphoproliferative disease that typically occurs in the earlier decades of life. The usual manifestation is painless massive cervical lymphadenopathy, although involvement of many extra nodal sites is common. This case illustrates Rosai-Dorman disease occurring in an elderly man with myelopathy and mass lesions of the cervical, thoracic, and lumbar spinal canal without typical lymphadenopathy.-
METHODS: Case report illustrating clinical presentation as well as radiographic and pathologic findings, including comparisons to cases previously reported.
RESULTS: Surgical decompression with incomplete resection of the lesion was performed, providing diagnosis and treatment guidance. The patient experienced significant neurologic improvement of myelopathy.
CONCLUSIONS: Recognizing clinical and laboratory features of this disease may permit earlier diagnosis and limit or avoid surgical intervention in some cases.
Author List
Hollowell JP, Wolfla CE, Shah NC, Mark LP, Whittaker MHAuthors
Leighton Mark MD Emeritus Professor in the Radiology department at Medical College of WisconsinChristopher E. Wolfla MD Professor in the Neurosurgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AgedCervical Vertebrae
Histiocytosis, Sinus
Humans
Magnetic Resonance Imaging
Male
Spinal Cord Diseases
