The neural representation of body part concepts. Cereb Cortex 2024 Jun 04;34(6)
Date
06/12/2024Pubmed ID
38863113Pubmed Central ID
PMC11166504DOI
10.1093/cercor/bhae213Scopus ID
2-s2.0-85195887945 (requires institutional sign-in at Scopus site)Abstract
Neuropsychological and neuroimaging studies provide evidence for a degree of category-related organization of conceptual knowledge in the brain. Some of this evidence indicates that body part concepts are distinctly represented from other categories; yet, the neural correlates and mechanisms underlying these dissociations are unclear. We expand on the limited prior data by measuring functional magnetic resonance imaging responses induced by body part words and performing a series of analyses investigating the cortical representation of this semantic category. Across voxel-level contrasts, pattern classification, representational similarity analysis, and vertex-wise encoding analyses, we find converging evidence that the posterior middle temporal gyrus, the supramarginal gyrus, and the ventral premotor cortex in the left hemisphere play important roles in the preferential representation of this category compared to other concrete objects.
Author List
Mazurchuk S, Fernandino L, Tong JQ, Conant LL, Binder JRAuthors
Jeffrey R. Binder MD Professor in the Neurology department at Medical College of WisconsinLeonardo Fernandino PhD Assistant Professor in the Neurology department at Medical College of Wisconsin
Jiaqing Tong Postdoctoral Researcher 2 in the Neurology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultBrain
Brain Mapping
Concept Formation
Female
Humans
Magnetic Resonance Imaging
Male
Semantics
Young Adult
