A Case of Disseminated Mycobacterium Haemophilum in a Kidney Transplant Recipient Presenting With Subcutaneous Nodules. WMJ 2024 Jul;123(3):233-237
Date
07/18/2024Pubmed ID
39024155Scopus ID
2-s2.0-85199126932 (requires institutional sign-in at Scopus site)Abstract
INTRODUCTION: Dermatologic manifestations of diseases in solid organ transplant recipients are common due to long-term immunosuppression.
CASE PRESENTATION: We present the case of a 63-year-old man with a kidney transplant who exhibited subcutaneous nodules on lower extremities, cytopenia, and asymptomatic pulmonary infiltrate. Through a skin biopsy and 16S ribosomal RNA (rRNA) sequencing, Mycobacterium haemophilum was identified. His clinical course was complicated by empyema, septic arthritis, and recurrence of his skin manifestations, despite ongoing antimicrobial treatment.
DISCUSSION: This case emphasizes the challenges and potential complications associated with M haemophilum infections in solid organ transplant recipients receiving long-term immunosuppressive therapy. It highlights the importance of employing advanced diagnostic techniques when evaluating dermatologic manifestations in these patients. The patient's complex clinical course also underscores the difficulties involved in effectively addressing and managing complications that may arise even after initiating therapy.
Author List
Li XR, Kumar D, Bo AY, Le JT, Ellis A, Young K, Wanat KA, Dhariwal M, Jha P, Green J, Aldrete SAuthors
Pinky Jha MD Associate Professor in the Medicine department at Medical College of WisconsinKarolyn A. Wanat MD Chair, Professor in the Dermatology department at Medical College of Wisconsin
Kara E. Young MD Associate Professor in the Dermatology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
HumansImmunocompromised Host
Kidney Transplantation
Male
Middle Aged
Mycobacterium Infections
Mycobacterium haemophilum
