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Small RNAs, but Sizable Itch: TRPA1 Activation by an Extracellular MicroRNA. Neuron 2018 Aug 08;99(3):421-422

Date

08/10/2018

Pubmed ID

30092208

DOI

10.1016/j.neuron.2018.07.040

Scopus ID

2-s2.0-85050581354 (requires institutional sign-in at Scopus site)   6 Citations

Abstract

Chronic itch is a major symptom of cutaneous T cell lymphoma (CTCL). In this issue of Neuron, Han and colleagues (2018) provide evidence that one of the itch mediators in CTCL is an extracellular miRNA that directly activates TRPA1 on sensory neurons.

Author List

Sheahan TD, Hachisuka J, Ross SE

Author

Tayler D. Sheahan PhD Assistant Professor in the Cell Biology Neurobiology and Anatomy department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Humans
MicroRNAs
Pruritus
Sensory Receptor Cells
TRPA1 Cation Channel
Transient Receptor Potential Channels