Review: Diagnostic Potential for Collaborative Pharyngitis Biomarkers. J Infect Dis 2024 Oct 23;230(Supplement_3):S190-S196
Date
10/23/2024Pubmed ID
39441193Pubmed Central ID
PMC11497841DOI
10.1093/infdis/jiae416Scopus ID
2-s2.0-85207597355 (requires institutional sign-in at Scopus site) 3 CitationsAbstract
Pharyngitis is an inflammatory condition of the pharynx and/or tonsils commonly seen in both children and adults. Viruses and bacteria represent the most common encountered etiologic agents-yeast/fungi and parasites are infrequently implicated. Some of these are predominantly observed in unique populations (eg, immunocompromised or unvaccinated individuals). This manuscript (part 3 of 3) summarizes the current state of biomarker diagnostic testing and highlights the expanding role they will likely play in the expedited diagnosis and management of patients with acute pharyngitis. Biomarkers, in conjunction with rapid antigen and/or nucleic acid amplification testing, will likely become the standard of care to accurately diagnose the etiologic agent(s) of pharyngitis. This novel testing paradigm has the potential to guide appropriate patient management and antibiotic stewardship by accurately determining if the cause of pharyngitis is due to a viral or bacterial etiology.
Author List
Ledeboer NA, Caldwell JM, Boyanton BL JrAuthor
Nathan A. Ledeboer PhD Chief, Professor in the Pathology and Laboratory Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BiomarkersChild
Humans
Nucleic Acid Amplification Techniques
Pharyngitis
