Review: Current Laboratory and Point-of-Care Pharyngitis Diagnostic Testing and Knowledge Gaps. J Infect Dis 2024 Oct 23;230(Supplement_3):S182-S189
Date
10/23/2024Pubmed ID
39441195Pubmed Central ID
PMC11497843DOI
10.1093/infdis/jiae415Scopus ID
2-s2.0-85207597145 (requires institutional sign-in at Scopus site) 9 CitationsAbstract
Pharyngitis is an inflammatory condition of the pharynx and/or tonsils commonly seen in both children and adults. Viruses and bacteria represent the most common encountered etiologic agents-yeast/fungi and parasites are infrequently implicated. Some of these are predominantly observed in unique populations (eg, immunocompromised or unvaccinated individuals). This manuscript (part 2 of 3) summarizes the current state of laboratory and point-of-care diagnostic testing and highlights the expanding role of nucleic acid amplification in the expedited diagnosis and management of patients with acute pharyngitis. It discusses preanalytical, analytical, and postanalytical variables that impact the performance of culture, rapid antigen, and nucleic acid amplification testing. Finally, it sets the stage for part 3, which discusses the emerging role of biomarkers in the management of individuals with acute pharyngitis.
Author List
Boyanton BL Jr, Caldwell JM, Ledeboer NAAuthor
Nathan A. Ledeboer PhD Chief, Professor in the Pathology and Laboratory Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BiomarkersDiagnostic Tests, Routine
Humans
Nucleic Acid Amplification Techniques
Pharyngitis
Point-of-Care Systems
Point-of-Care Testing
