Acute and chronic radiation injury. J Vasc Surg 2011 Jan;53(1 Suppl):15S-21S
Date
09/17/2010Pubmed ID
20843630DOI
10.1016/j.jvs.2010.06.175Scopus ID
2-s2.0-78650552590 (requires institutional sign-in at Scopus site) 180 CitationsAbstract
INTRODUCTION: Although all areas of the body are susceptible to radiation injury, different tissues have varying tolerances for radiation exposure. The goal of this summary is to introduce basic concepts of radiation biology and discuss the effects of radiation on various tissues.
METHODS: Reference texts and literature were reviewed to summarize key points in radiation biology and the direct and indirect cell damage caused by radiation.
RESULTS: The most prevalent factor for injury is long exposure time, which can be an issue in lengthy peripheral vascular or aortic interventions. Several key maneuvers can help decrease exposure for both the patient and the physician.
CONCLUSION: Radiation induces tissue injury at the cellular level. The use of good fluoroscopic technique is imperative for physician and patient protection.
Author List
Brown KR, Rzucidlo EAuthor
Kellie R. Brown MD Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Acute DiseaseCataract
Cell Cycle
Cell Death
Chronic Disease
Fluoroscopy
Humans
Neoplasms, Radiation-Induced
Occupational Exposure
Radiation Dosage
Radiation Injuries
Radiobiology
Radiodermatitis
Radiography, Interventional
Reactive Oxygen Species
Skin
Vascular Surgical Procedures
