Faculty Collaboration Database

Drug-induced immune cytopenias. Toxicology 2005 Apr 15;209(2):149-53

Date

03/16/2005

Pubmed ID

15767027

DOI

10.1016/j.tox.2004.12.031

Scopus ID

2-s2.0-17644413243 (requires institutional sign-in at Scopus site)   82 Citations

Abstract

Drugs can induce thrombocytopenia by several mechanisms, including marrow suppression and destruction of platelets in the peripheral blood by non-immune and immune mechanisms. We will review here current understanding of the immune mechanisms by which drugs promote immune-mediated platelet destruction resulting in thrombocytopenia.

Author List

Aster RH

MESH terms used to index this publication - Major topics in bold

Animals
Autoantibodies
Blood Platelets
Drug Hypersensitivity
Drug-Related Side Effects and Adverse Reactions
Humans
Thrombocytopenia