Postoperative Considerations Following Pituitary Surgery: A Guide for Clinicians. Endocr Pract 2025 Oct;31(10):1339-1345
Date
07/01/2025Pubmed ID
40581268DOI
10.1016/j.eprac.2025.06.018Scopus ID
2-s2.0-105012370564 (requires institutional sign-in at Scopus site)Abstract
Transsphenoidal surgery represents the primary treatment for pituitary adenomas (other than prolactin-secreting) and other sellar/suprasellar masses including craniopharyngiomas. Endocrine evaluation for anterior hypopituitarism and water metabolism disorders is indicated in all patients. Transient fluid restriction postoperatively in patients without vasopressin deficiency reduces the risk of hyponatremia and hospital readmission. In Cushing disease, the postoperative serum cortisol levels in the first postoperative days guide further management. In acromegaly, remission is established primarily by insulin-like growth factor-1 measurement 3 months postoperatively. Patients with functioning adenomas require proactive management of comorbidities related to hormone excess and lifelong monitoring for recurrence. Surgical outcomes are superior at high-volume institutions with neurosurgical and endocrinological expertise.
Author List
Giraldi EA, Ioachimescu AGAuthor
Adriana G. Ioachimescu MD, PhD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdenomaHumans
Pituitary Gland
Pituitary Neoplasms
Postoperative Care
Postoperative Complications
Postoperative Period
