Medical College of Wisconsin
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Pathogenesis of calcium pyrophosphate crystal deposition disease. Curr Rheumatol Rep 2001 Feb;3(1):17-23

Date

03/20/2001

Pubmed ID

11177767

DOI

10.1007/s11926-001-0046-x

Scopus ID

2-s2.0-0035260412 (requires institutional sign-in at Scopus site)   14 Citations

Abstract

Calcium pyrophosphate dihydrate deposition (CPPDD) disease is an increasingly common form of arthritis affecting the elderly. It is characterized by the formation of CPPD crystals in articular cartilage and usually results in severe cartilage destruction with loss of joint function. This article discusses our understanding of how and why these crystals form, highlighting recent developments in the field.

Author List

Rosenthal AK

Author

Ann K. Rosenthal MD Associate Dean, Chief, Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aged
Cartilage, Articular
Chondrocalcinosis
Crystallization
Humans
Transglutaminases