Pathogenesis of calcium pyrophosphate crystal deposition disease. Curr Rheumatol Rep 2001 Feb;3(1):17-23
Date
03/20/2001Pubmed ID
11177767DOI
10.1007/s11926-001-0046-xScopus ID
2-s2.0-0035260412 (requires institutional sign-in at Scopus site) 14 CitationsAbstract
Calcium pyrophosphate dihydrate deposition (CPPDD) disease is an increasingly common form of arthritis affecting the elderly. It is characterized by the formation of CPPD crystals in articular cartilage and usually results in severe cartilage destruction with loss of joint function. This article discusses our understanding of how and why these crystals form, highlighting recent developments in the field.
Author List
Rosenthal AKAuthor
Ann K. Rosenthal MD Associate Dean, Chief, Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedCartilage, Articular
Chondrocalcinosis
Crystallization
Humans
Transglutaminases