Medical College of Wisconsin
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Wanting, Liking, and Missing Out: Exploring the Role of Reward Functioning in the Overlap Between PTSD and Depression. J Nerv Ment Dis 2022 Jul 01;210(7):497-503

Date

06/30/2022

Pubmed ID

35766543

DOI

10.1097/NMD.0000000000001456

Scopus ID

2-s2.0-85133214545 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

Diminished reward functioning (anhedonia) is an aspect of multiple psychiatric diagnoses and is a critical component of depression, yet it has rarely been examined in the context of posttraumatic stress disorder (PTSD). Deficits in reward function may be a transdiagnostic factor contributing to the high rate of comorbidity between PTSD and depression. The present study examined the commonality and distinction between PTSD and depression and their relationship to reward functioning using a bifactor model in a sample of 106 trauma-exposed undergraduates. Results indicated a strong commonality factor between PTSD and depression. Of three indices of reward functioning (i.e., hedonic pleasure, reward motivation, and environmental reward availability), environmental reward availability alone was related to unique latent factors for PTSD and depression, and their commonality. Findings suggest that environmental context may be the key to understanding the role of reward in PTSD, depression, and psychopathology broadly.

Author List

Olin CC, McDevitt-Murphy ME, Leonard SJ, Acuff SF

Author

Cecilia C. Olin PhD, MS Assistant Professor in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Anhedonia
Depression
Humans
Motivation
Reward
Stress Disorders, Post-Traumatic