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Neurotoxic Implications of Vincristine in Pediatric: Ophthalmology: A Case Series. J Pediatr Ophthalmol Strabismus 2025;62(4):e51-e53

Date

07/23/2025

Pubmed ID

40700301

DOI

10.3928/01913913-20250530-01

Scopus ID

2-s2.0-105012118852 (requires institutional sign-in at Scopus site)

Abstract

The authors report a retrospective case series of three pediatric patients receiving vincristine who developed varying degrees and laterality of ptosis and abduction deficits. Treatment for these patients included use of thiamine, pyridoxine, and adjusting vincristine administration. These cases add to the variability of findings and treatment of vincristine neurotoxicity. [J Pediatr Ophthalmol Strabismus. 2025;62(4):e51-e53.].

Author List

Adhan IK, Martin J, Strombeck T, Chisholm SAM, Stiff H

Authors

Smith Ann Meile Chisholm MD Assistant Professor in the Ophthalmology department at Medical College of Wisconsin
Jacob S. Martin MD Assistant Professor in the Ophthalmology department at Medical College of Wisconsin
Heather Stiff MD Assistant Professor in the Ophthalmology department at Medical College of Wisconsin
Tracey J. Strombeck OD Assistant Professor in the Ophthalmology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Antineoplastic Agents, Phytogenic
Blepharoptosis
Child
Child, Preschool
Female
Humans
Infant
Male
Neurotoxicity Syndromes
Retrospective Studies
Vincristine