Pancreatitis in children. J Pediatr Gastroenterol Nutr 2003 Nov;37(5):591-5
Date
10/29/2003Pubmed ID
14581803DOI
10.1097/00005176-200311000-00017Scopus ID
2-s2.0-1542494459 (requires institutional sign-in at Scopus site) 222 CitationsAbstract
OBJECTIVES: To determine the incidence, etiology and outcome of pancreatitis at a regional children's hospital.
METHODS: Chart review of all patients with pancreatitis seen during a 6 year period at the Children's Hospital of Wisconsin. The diagnosis of pancreatitis required either a serum amylase or lipase >3 times normal or radiographic evidence of pancreatitis.
RESULTS: Two hundred fourteen episodes of pancreatitis in 180 patients were documented. The most common etiologies were systemic disease (14%), trauma (14%), drug induced (12%), biliary tract disease (12%), infectious (8%), and idiopathic (8%), which made up 68% of the total cases. Eleven patients died, all from underlying systemic illnesses. The serum amylase and lipase were elevated in 82% and 83% of patients respectively.
CONCLUSIONS: Pancreatitis is more common in children than previously thought. Upon careful assessment fewer cases were found to be idiopathic than in previous series. The outcome of pancreatitis depends on co-morbid conditions.
Author List
Werlin SL, Kugathasan S, Frautschy BCAuthor
Steven L. Werlin MD Emeritus Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Abdominal PainAdolescent
Amylases
Biliary Tract Diseases
Child
Child, Preschool
Hospitals, Pediatric
Humans
Infant
Lipase
Pancreas
Pancreatitis
Prognosis
Valproic Acid
