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Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture. DNA Seq 2002 Jun;13(3):133-7

Date

10/24/2002

Pubmed ID

12391722

DOI

10.1080/10425170290023428

Scopus ID

2-s2.0-0036320052   4 Citations

Abstract

The cDNA encoding human heme-regulated eukaryotic initiation factor-2 alpha (eIF-2 alpha) kinase was cloned from a human bone marrow culture. Its deduced amino acid sequence comprised of 629 amino acids with a calculated molecular weight of 71,031 Da. RT-PCR analysis revealed that the gene was also expressed in heart, kidney, spleen, muscle, and stomach.

Author List

Omasa T, Chen YG, Mantalaris A, Tsai YC, Wu JH

Author

Yi-Guang Chen PhD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Amino Acid Sequence
Animals
Base Sequence
Bone Marrow Cells
Cloning, Molecular
Conserved Sequence
Humans
Mice
Molecular Sequence Data
Organ Specificity
Rabbits
Rats
Sequence Alignment
eIF-2 Kinase