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Computing oxygen-enhanced ventilation maps using correlation analysis. Magn Reson Med 2003 Mar;49(3):591-4

Date

02/21/2003

Pubmed ID

12594766

DOI

10.1002/mrm.10395

Scopus ID

2-s2.0-12244305600   27 Citations

Abstract

Correlation maps of oxygen-enhanced ventilation were obtained in nine healthy volunteers using complete and selected image series. The complete series included all images acquired with the subjects alternately inhaling room air and 100% oxygen. The selected series were the subsets of the complete series and included only co-registered images that showed matched diaphragmatic position at maximal expiration. Cross-correlation was computed between the time response function of each pixel and the input function representing the alternation between periods of room air and 100% oxygen inhalation. The confidence level for the correlation analysis was set to 0.01. Pulmonary parenchymal anatomy was consistently reproduced throughout the lung, even in anterior slices where published data have reported correlation problems. The overall average correlation coefficient was 0.66 +/- 0.07 for the complete series and 0.75 +/- 0.08 for the selected series. It was concluded that correlation analysis could be used to reconstruct qualitative oxygen-enhanced ventilation maps.

Author List

Mai VM, Tutton S, Prasad PV, Chen Q, Li W, Chen C, Liu B, Polzin J, Kurucay S, Edelman RR

Author

Sean Tutton MD Vice Chair, Professor in the Radiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Analysis of Variance
Diaphragm
Female
Humans
Image Enhancement
Lung
Magnetic Resonance Imaging
Male
Oxygen
Pulmonary Ventilation
jenkins-FCD Prod-480 9a4deaf152b0b06dd18151814fff2e18f6c05280