Pediatric Orbital High-Grade B-Cell Lymphoma: A Case Report and Review of the Literature. Ophthalmic Plast Reconstr Surg 2025 Jul-Aug 01;41(4):e120-e122
Date
12/24/2024Pubmed ID
39718145Pubmed Central ID
PMC12185768DOI
10.1097/IOP.0000000000002885Scopus ID
2-s2.0-85214374945 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Ocular involvement of lymphoma may present as a primary orbital or intraocular lymphoma or as a manifestation of metastatic disease. Involvement of various ocular structures may be difficult to diagnose due to its rarity and nonspecific clinical presentation. Primary high-grade B-cell lymphoma with MYC and BCL2 rearrangements of the orbit has rarely been reported in the adult population and has not previously been reported in the pediatric population. Herein the authors present a unique case of orbital high-grade B-cell lymphoma in a pediatric patient, initially diagnosed as preseptal cellulitis. Careful observation and escalation of care ultimately led to the accurate diagnosis and complete remission of the disease.
Author List
Nguyen KK, Regner MF, Olson SB, Ng JDAuthor
Michael Regner MD Associate Professor in the Radiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BiopsyChild
Diagnosis, Differential
Humans
Lymphoma, B-Cell
Lymphoma, Large B-Cell, Diffuse
Magnetic Resonance Imaging
Orbital Neoplasms
Tomography, X-Ray Computed
