Burkitt Lymphoma Presenting as an Intracardiac Mass: Case Report and Review of Literature. Am J Case Rep 2016 Aug 03;17:553-8
Date
08/04/2016Pubmed ID
27484990Pubmed Central ID
PMC4973801DOI
10.12659/ajcr.899022Scopus ID
2-s2.0-84985014346 (requires institutional sign-in at Scopus site) 12 CitationsAbstract
BACKGROUND Non-neoplastic causes such as infections and thrombi account for most intracardiac masses. Primary tumors such as myxomas and metastasis from breast cancer, lung cancer, or melanomas account for many of the remaining cases. Burkitt lymphoma manifesting as an intracardiac mass is a rare entity, with 21 cases reported in the English literature. CASE REPORT We report the case of a man infected with human immunodeficiency virus (HIV) who presented with non-specific cardiac symptoms and was later found to have intracardiac mass caused by Burkitt lymphoma. His rapid decline with unexpected complications was reversed with prompt management. Subsequent to induction, the patient achieved a near complete response with considerable improvement in his condition. CONCLUSIONS Lymphoma should be considered in the differential diagnosis of intracardiac masses. Associated cardiac symptoms are frequently non-specific and can often be overlooked or underappreciated. Burkitt lymphoma has a short doubling time and an intracardiac lesion can become life-threatening in a matter of days. Early recognition and prompt treatment are crucial to achieving optimal outcomes.
Author List
Chan O, Igwe M, Breburda CS, Amar SAuthor
Christian Steve Breburda PhD, MD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultBurkitt Lymphoma
Echocardiography, Three-Dimensional
HIV Infections
Heart Neoplasms
Humans
Male
Tomography, X-Ray Computed
