Case Series of Deep-Seated Pyogenic Granulomas in Pediatric Patients. Pediatr Dermatol 2025 Oct 14
Date
10/15/2025Pubmed ID
41087026DOI
10.1111/pde.70012Scopus ID
2-s2.0-105018792150 (requires institutional sign-in at Scopus site)Abstract
Deep-seated pyogenic granulomas (DSPG) are a rare variant of pyogenic granulomas and are commonly mistaken for other entities. Often, DSPG present as blue papulonodules without ulceration, and their clinical and histologic appearance can mimic other common subcutaneous nodules seen in pediatric patients, including hemangiomas, venous malformations, pilomatricomas, and kaposiform hemangioendotheliomas. Herein, we describe the clinical and histologic features of six pediatric cases of DSPG, as the clinicopathologic correlation of DSPG is scarce in the literature, especially in pediatric patients.
Author List
Casale F, North P, Chiu YE, Chun R, Humphrey SR, Lalor L, Plunk M, Carlberg VAuthors
Valerie M. Carlberg MD Associate Professor in the Dermatology department at Medical College of WisconsinYvonne E. Chiu MD Vice Chair, Professor in the Dermatology department at Medical College of Wisconsin
Robert H. Chun MD Professor in the Otolaryngology department at Medical College of Wisconsin
Stephen R. Humphrey MD Associate Professor in the Dermatology department at Medical College of Wisconsin
Leah Lalor MD Associate Professor in the Dermatology department at Medical College of Wisconsin
Paula E. North MD, PhD Professor in the Pathology department at Medical College of Wisconsin









