Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Case Series of Deep-Seated Pyogenic Granulomas in Pediatric Patients. Pediatr Dermatol 2025 Oct 14

Date

10/15/2025

Pubmed ID

41087026

DOI

10.1111/pde.70012

Scopus ID

2-s2.0-105018792150 (requires institutional sign-in at Scopus site)

Abstract

Deep-seated pyogenic granulomas (DSPG) are a rare variant of pyogenic granulomas and are commonly mistaken for other entities. Often, DSPG present as blue papulonodules without ulceration, and their clinical and histologic appearance can mimic other common subcutaneous nodules seen in pediatric patients, including hemangiomas, venous malformations, pilomatricomas, and kaposiform hemangioendotheliomas. Herein, we describe the clinical and histologic features of six pediatric cases of DSPG, as the clinicopathologic correlation of DSPG is scarce in the literature, especially in pediatric patients.

Author List

Casale F, North P, Chiu YE, Chun R, Humphrey SR, Lalor L, Plunk M, Carlberg V

Authors

Valerie M. Carlberg MD Associate Professor in the Dermatology department at Medical College of Wisconsin
Yvonne E. Chiu MD Vice Chair, Professor in the Dermatology department at Medical College of Wisconsin
Robert H. Chun MD Professor in the Otolaryngology department at Medical College of Wisconsin
Stephen R. Humphrey MD Associate Professor in the Dermatology department at Medical College of Wisconsin
Leah Lalor MD Associate Professor in the Dermatology department at Medical College of Wisconsin
Paula E. North MD, PhD Professor in the Pathology department at Medical College of Wisconsin