Staged resection for a ruptured hepatoblastoma: a 6-year follow-up. Pediatr Surg Int 2007 Jun;23(6):609-11
Date
10/27/2006Pubmed ID
17066271DOI
10.1007/s00383-006-1827-0Scopus ID
2-s2.0-34249069584 (requires institutional sign-in at Scopus site) 12 CitationsAbstract
Hepatoblastoma (HB) is a rare germ cell tumour of childhood usually presenting with progressive abdominal distention. However, presentation as acute abdomen is a rare occurrence and is secondary to spontaneous rupture. This presentation carries high mortality. To our knowledge, six cases of ruptured hepatoblastoma have previously been reported, although the long-term outcome has not been clear. We report a case of ruptured HB who was managed by initial control of haemorrhage by laparotomy followed by chemotherapy with high-risk hepatoblastoma protocol as per SIOPEL 2 (cisplatin, carboplatin and doxorubicin) and a staged hepatectomy 5 months later. Patient is currently disease free at 6-year follow-up. Staged hepatectomy after initial control of haemorrhage does not preclude a curative resection.
Author List
Madanur MA, Battula N, Davenport M, Dhawan A, Rela MAuthor
Narendra Battula MD Associate Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Antineoplastic Combined Chemotherapy ProtocolsChemotherapy, Adjuvant
Gastrointestinal Hemorrhage
Hepatectomy
Hepatoblastoma
Humans
Infant
Liver Neoplasms
Male
Rupture, Spontaneous
