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Radiation-induced Cataracts in Children With Brain Tumors Receiving Craniospinal Irradiation. J Pediatr Hematol Oncol 2018 May;40(4):304-305

Date

04/06/2018

Pubmed ID

29621062

DOI

10.1097/MPH.0000000000001142

Scopus ID

2-s2.0-85046293330 (requires institutional sign-in at Scopus site)   9 Citations

Abstract

Radiation is a well-known cause of the development of cataracts. For children with brain tumors, craniospinal irradiation (CSI) would be expected to result in a significant risk of cataract development. We reviewed the incidence of cataracts in children with brain tumors who received CSI at our institution. Of 45 children who received CSI and had ophthalmologic examinations, 13 developed cataracts. The median time to develop cataracts was 27.6 months. Seven children underwent surgery for cataract. Given this high incidence of cataracts, we suggest routine eye examinations for all children receiving CSI.

Author List

Whelan RJ, Saccomano B, King R, Dorris K, Hemenway M, Hankinson TC, Liu AK

Author

Ros J. Whelan MBBS Assistant Professor in the Neurosurgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Brain Neoplasms
Cataract
Child
Child, Preschool
Craniospinal Irradiation
Female
Follow-Up Studies
Humans
Incidence
Male
Radiation Injuries
Retrospective Studies