Mechanisms of pain. Proc Natl Acad Sci U S A 2001 Oct 09;98(21):11845-6
Date
09/20/2001Pubmed ID
11562504Pubmed Central ID
PMC59728DOI
10.1073/pnas.211373398Scopus ID
2-s2.0-0035834013 (requires institutional sign-in at Scopus site) 107 CitationsAbstract
Persistent or chronic pain is the primary reason people seek medical care, yet current therapies are either inadequate for certain types of pain or cause intolerable side effects. Recently, pain neurobiologists have identified a number of cellular and molecular processes that lead to the initiation and maintenance of pain. Understanding these underlying mechanisms has given significant promise for the development of more effective, more specific pain therapies in the near future.
Author List
Stucky CL, Gold MS, Zhang XAuthor
Cheryl L. Stucky PhD Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
HumansMorphine
Neuronal Plasticity
Neurons, Afferent
Nociceptors
Pain
Public Health
Receptors, Drug
Research
Signal Transduction
TRPV Cation Channels