Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Rat genetics: attaching physiology and pharmacology to the genome. Nat Rev Genet 2002 Jan;3(1):33-42

Date

02/02/2002

Pubmed ID

11823789

DOI

10.1038/nrg702

Scopus ID

2-s2.0-0036250938 (requires institutional sign-in at Scopus site)   223 Citations

Abstract

During the past five years, the Rat Genome Project has been rapidly gaining momentum, especially since the announcement in August 2000 of plans to sequence the rat genome. Combined with the wealth of physiological and pharmacological data for the rat, the genome sequence should facilitate the discovery of mammalian genes that underlie the physiological pathways that are involved in disease. Most importantly, this combined physiological and genomic information should also lead to the development of better pre-clinical models of human disease, which will aid in the development of new therapeutics.

Author List

Jacob HJ, Kwitek AE

Author

Anne E. Kwitek PhD Professor in the Physiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Disease Models, Animal
Genome
Humans
Pharmacology
Physiology
Quantitative Trait, Heritable
Rats