Medical College of Wisconsin
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Idiopathic pulmonary fibrosis. A rare cause of scintigraphic ventilation-perfusion mismatch. Clin Nucl Med 1990 May;15(5):321-3

Date

05/01/1990

Pubmed ID

2340674

Scopus ID

2-s2.0-0025283874 (requires institutional sign-in at Scopus site)   6 Citations

Abstract

A case of idiopathic pulmonary fibrosis with multiple areas of mismatch on ventilation-perfusion lung imaging in the absence of pulmonary embolism is presented. Idiopathic pulmonary fibrosis is one of the few nonembolic diseases producing a pulmonary ventilation-perfusion mismatch. In this condition, chest radiographs may not detect the full extent of disease, and xenon-133 ventilation imaging may be relatively insensitive to morbid changes in small airways. Thus, when examining patients with idiopathic pulmonary fibrosis, one should be aware that abnormal perfusion imaging patterns without matching ventilation abnormalities are not always due to embolism. In this setting, contrast pulmonary angiography is often needed for accurate differential diagnosis.

Author List

Pochis WT, Krasnow AZ, Collier BD, Mewissen MW, Almagro UA, Hellman RS, Isitman AT



MESH terms used to index this publication - Major topics in bold

Diagnosis, Differential
Humans
Male
Middle Aged
Pulmonary Artery
Pulmonary Embolism
Pulmonary Fibrosis
Pulmonary Veins
Radiography
Radionuclide Imaging
Ventilation-Perfusion Ratio
Xenon Radioisotopes